Inhibition of human lung cancer cell proliferation and survival by wine
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Date
Authors
Barron, Carly
Moore, Jesse
Tsakiridis, Theodoros
Pickering, Gary
Tsiani, Evangelia
Journal Title
Journal ISSN
Volume Title
Publisher
BioMed Central
Abstract
Compounds of plant origin and food components have attracted scientific attention for use as agents for cancer prevention and treatment. Wine contains polyphenols that were shown to have anti-cancer and other health benefits. The survival pathways of Akt and extracellular signal-regulated kinase (Erk), and the tumor suppressor p53 are key modulators of cancer cell growth and survival. In this study, we examined the effects of wine on proliferation and survival of human Non-small cell lung cancer (NSCLC) cells and its effects on signaling events.
Description
Compounds of plant origin and food components have attracted scientific attention for use as
agents for cancer prevention and treatment. Wine contains polyphenols that were shown to have anti-cancer and
other health benefits. The survival pathways of Akt and extracellular signal-regulated kinase (Erk), and the tumor
suppressor p53 are key modulators of cancer cell growth and survival. In this study, we examined the effects of
wine on proliferation and survival of human Non-small cell lung cancer (NSCLC) cells and its effects on signaling
events.