DEVELOPMENT OF A SYNTHETIC PROTOCOL FOR THE PREPARATION OF MONO-SUBSTITUTED N-3 FUNCTIONALIZED SYDNONES

Abstract

This work explores new catalytic methodologies for the synthesis of N-3 monosubstituted sydnone compounds. Sydnones are widely studied for their chemical behaviour, biological and physical properties, and are the most popular mesoionic compounds. Despite the popularity of sydnones, there are still many unexplored approaches for their synthesis and application. Herein is described a simple, novel, one-pot catalytic procedure for the preparation of sydnones. This method utilizes inexpensive commercially available reagents and mild reaction conditions.